Pharmacoeconomics: theory and practice
№1, 2020, Vol.8

Analytical review of sources of scientific information and analysis of drug therapy based on the medical histories of patients in the occupational pathology Department of the hospital indicate that the scientific justification for the development of a unified system of interrelated assessments, quality indicators and economic characteristics of medical and medicinal care requires the establishment of scientifically based approaches to their nomenclature and volume. Among occupational diseases, a significant share is occupied by pathology of the musculoskeletal system, caused by overstrain and microtavmatization of organs and systems. It is established that occupational diseases are directly related to early diagnosis and treatment and prevention measures, and one of the most important measures is their early detection during preventive medical examinations. In recent years, pharmacoeconomics research has emerged as a serious scientific field with its own methodology and appropriate tools. In this regard, pharmacoeconomical assessment of patient treatment technology becomes an important source of information that helps in making managerial decisions in healthcare. For managers of pharmacies in medical organizations, one of the most important tasks is the rational formation and effective use of the range of medicines for the treatment of inpatient patients. The optimal solution to this problem depends on many factors, among which the volume of financial resources of medical organizations and the prevalence of certain diseases are of primary importance.

Type 1 diabetes is an autoimmune disease of the endocrine system, characterized by absolute insulin deficiency. Diabetes control is currently carried out by delivering insulin in a basic bolus insulin therapy regimen by repeated injections of insulin using a syringe pen or continuous subcutaneous infusion of insulin with insulin pumps with the possibility of continuous monitoring of blood glucose levels. The use of insulin pumps is more effective than multiple insulin injections. In order to achieve a high level of quality of life for patients. This article describes the development of insulin pumps in patients with type 1 diabetes.

This article discusses the issues of pharmacoeconomic modeling related to the description of the movement of patients in the pharmacoeconomic model, as well as approaches to determining the course dose of drugs under the condition of integer calculations. In particular, we described two possible ways of distributing patients between treatment regimens in pharmacoeconomic models, also analyzed the effects of simultaneous and uniform entry of patients into the model. As part of the issue of determining the course dose of a drug, we described the limitations and possibilities of calculations based on the active substance and packaging, as well as the transition factor of the remainder of the drug in the next time period.