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Evaluation of the cost-effectiveness of insulin therapy and glycemic control methods in type 1 diabetes mellitus: historical aspects and modern approaches
INTRODUCTION. Type 1 diabetes mellitus requires lifelong insulin therapy, which leads to significant healthcare system costs. The emergence of new technologies for diabetes control determines the need to evaluate their cost-effectiveness.
AIM. To study the historical aspects and modern trends in economic evaluation of insulin therapy in type 1 diabetes mellitus.
MATERIALS AND METHODS. A search for publications was conducted in the databases of medical and biological publications of the US National Library of Medicine, “eLIBRARY,” and “CYBERLENINCA” using keywords related to type 1 diabetes mellitus and various aspects of economic evaluation.
RESULTS AND DISCUSSION. Analysis has shown that economic evaluation methods for diabetes developed in parallel with treatment technologies: from simple cost calculations for educational programs in the 1980s to the creation of complex models such as the CORE Diabetes Model and Sheffield Type 1 Diabetes Policy Model. The main research directions were identified: evaluation of early diagnosis of complications, comparison of multiple daily insulin injection regimens and continuous subcutaneous insulin infusion, economic assessment of continuous glucose monitoring, and analysis of insulin analogs usage. The key role of longterm modeling for predicting the impact of various therapy methods on the development of complications and patients’ quality of life has been established.
CONCLUSIONS. Promising research directions include assessment of telemedicine monitoring costs, adaptation of models for the Russian healthcare
system, and studying the impact of glycemic variability on the cost-effectiveness of treatment.
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Bibliography link:
Grazhdankina A.A., Karakulova E.V. Evaluation of the cost-effectiveness of insulin therapy and glycemic control methods in type 1 diabetes mellitus: historical aspects and modern approaches // Pharmacoeconomics: theory and practice. - 2025. - Vol.13, №2. P. 5-11 DOI: https://doi.org/10.30809/phe.2.2025.1
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