Krylov V.A. 498

Practical implementation of indirect comparison methodology

This article describes the currently used methods of indirect comparisons. The possibilities of using adjusted indirect comparison by the «Bucher method» are considered in detail. An indirect comparison of menotropin vs follitropin - alpha + menotropin is performed on the K. Buhler clinical trial. The indirect comparison showed no statistically significant differences between menotropin and follitropin-alpha + menotropin: OR=0.92 (0.68; 1.24), RR=0.93 (0.71;1.21).
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