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Complicated intra-abdominal infection at multidisciplinary hospital: economics of real practice of antimicrobial treatment
Aim: To assess economic efficiency of complicated intra-abdomibal infections treatment in real practice compared to alternative scenario (treatment with carbapenem
Ertapanem) taking in to account E. coli resistance. Methods: Cost-effectiveness analysis were performed. Mathematic modelling was done to assess prognosis
of bacterial resistance. Results: Cost of 1 case of complicated intra-abdomibal infections in real practice is 83048,08 rub compared to 91706,06 rub according to
alternative strategy. Cost-effectiveness analysis revealed that real practice of treatment intra-abdomibal infections dominated alternative scenario: less effectiveness
lead to lower cost. Additional effectiveness (1,95%) demand additionally 443316,97 rub. Taking into account dynamic of E. Coli resistance ICER during 2011-2015
period decreased up to 40%. Conclusion: Antimicrobial resistance of bacterial agents is important criteria which should be used to estimate economic effectiveness
of any medical strategy.
Key words: complicated intra-abdominal infection, bacterial resistance, pharmacoeconomic analysis
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Bibliography link:
Y. M. Gomon, A. S. Kolbin, Y. E. Balykina, M. A. Arepiyeva, S. V. Sidorenko, V. V. Strizheletskiy. I. G. Ivanov, Y. V. Lobzin Complicated intra-abdominal infection at multidisciplinary hospital: economics of real practice of antimicrobial treatment // Pharmacoeconomics: theory and practice. - 2018. - Vol.6, №1. - P.10-20 DOI: https://doi.org/10.30809/phe.1.2018.2
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